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:: Volume 3, Issue 4 (Winter 2025) ::
Health Res Develop 2025, 3(4): 56-63 Back to browse issues page
Effect of Total Knee Arthroplasty on Quality of Life in Patients Aged 60–70 Years with Advanced Osteoarthritis: A Clinical Study
Reza Noktehsanj , Ali Nami *1 , Mohammadali Jafarizare , Arsalan Lazemi zare
1- & Department of Surgery, School of Medicine, Fatemi Hospital, Ardabil University of Medical Sciences, Ardabil, Iran. , ali.nami.damirchi@gmail.com
Abstract:   (115 Views)
Background: Patient-reported outcomes (PROs) have recently played a crucial role in evaluating the results of total knee arthroplasty (TKA), enabling precise assessment of changes in quality of life, pain, and physical function. Among the commonly used tools in orthopedic studies, the WOMAC and Oxford Knee Score (OKS) questionnaires are most frequently employed. The aim of this study was to evaluate the impact of TKA on the quality of life of patients aged 60–70 years with advanced knee osteoarthritis.
Methods: This interventional pre–post study without a control group was conducted on 78 patients with advanced knee osteoarthritis who underwent unilateral TKA. Demographic information was recorded using a standardized checklist, and the WOMAC and OKS questionnaires were completed before surgery and three months postoperatively. Changes in quality of life, pain, joint stiffness, and physical function were compared and analyzed statistically.
Results: Of the total sample, 44.9% were male, 21.8% had university-level education, 67.9% lived in urban areas, and 48.7% were employed. After surgery, the mean OKS score decreased from 21.97 preoperatively to 36.74 postoperatively. Pain scores decreased from 8.50 to 3.27, and joint stiffness scores decreased from 3/87 to 1/68. Physical function scores improved significantly, increasing from 24/13 to 12/27. There were no significant differences in overall WOMAC scores, its subscales, or OKS scores between men and women.
Conclusion: The results of this study indicate that although TKA in patients aged 60–70 years led to reduced pain, decreased joint stiffness, and improved physical function, the OKS-based quality of life score declined postoperatively, and no significant improvement was observed in this measure. This suggests that, despite improvements in some functional outcomes, the perceived quality of life of patients after surgery does not necessarily increase and warrants further investigation into factors influencing this lack of improvement.
Keywords: knee joint replacement, knee osteoarthritis, quality of life
Full-Text [PDF 747 kb]   (17 Downloads)    
Type of Study: Original | Subject: Special
Received: 2025/09/15 | Accepted: 2025/11/3 | Published: 2025/12/31
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noktehsanj R, nami A, jafarizare M, lazemi zare A. (2025). Effect of Total Knee Arthroplasty on Quality of Life in Patients Aged 60–70 Years with Advanced Osteoarthritis: A Clinical Study. Health Res Develop. 3(4), 56-63.
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Volume 3, Issue 4 (Winter 2025) Back to browse issues page
پژوهش و توسعه سلامت Health research and development
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