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Comparison of platelet level, hemoglobin and platelet-to-hemoglobin ratio in patients with diabetic foot ulcers and diabetic patients without ulcers in Imam Khomeini Hospital in Ardabil city in 2022
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Bita Rahmani1    , Ahmad Ghasemi *2 |
1- azad ardabil
2- azad ardabil , ahmadghasemi720@gmail.com |
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Abstract: (27 Views) |
Background: Diabetes is one of the most common metabolic diseases worldwide, with an increasing annual prevalence and multiple complications. One of the most important and dangerous complications is diabetic foot ulcer, which leads to a higher risk of amputation and mortality. Previous studies have shown that hematologic indices such as hemoglobin and platelet count can be effective in predicting this complication. This study aimed to compare the levels of platelet, hemoglobin, and the PHR index in diabetic patients with and without diabetic foot ulcers.
methods: This case-control study was conducted on 200 patients with diabetic foot ulcers and 200 patients without ulcers, hospitalized at Imam Khomeini Hospital, Ardabil. The patients were matched for age and sex. Data analysis was performed using SPSS version 21, employing independent t-tests and Mann-Whitney tests to assess differences between the two groups. A significance level of less than 0.05 was considered.
Results: There was no significant difference between the two groups regarding sex and age. The mean hemoglobin in the group without foot ulcers (13.6 ± 0.3) was significantly higher than in the group with foot ulcers (10.75 ± 0.29) (p = 0.001). The mean platelet count in the group without foot ulcers (299,053.61 ± 102,684.21) was significantly lower than in the group with foot ulcers (353,675.64 ± 103,281.59) (p = 0.001). Additionally, the mean PHR index in the group without foot ulcers (22,008.93 ± 7,570.17) was significantly lower than in the group with foot ulcers (32,921.21 ± 9,663.53) (p = 0.001).
Conclusion: The present study showed that platelet, hemoglobin, and PHR indices can be considered as predictive factors for diabetic foot ulcers, and their regular evaluation in diabetic patients is of great importance. |
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| Keywords: Diabetic foot ulcer, Platelet count, PHR index |
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Type of Study: Original |
Subject:
Special
Received: 2025/09/3 | Accepted: 2025/09/28
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